Myasthenia gravis is a chronic disorder characterized by weakness
and rapid fatigue of any of the muscles under your voluntary control.
It's caused by a breakdown in the normal communication between nerves
Myasthenia gravis (MG) is a chronic autoimmune
disorder that results in progressive skeletal muscle weakness. MG
causes rapid fatigue (fatigability) and loss of strength upon exertion
that improves after rest. Myasthenia gravis is caused by a defect
in the transmission of nerve impulses to muscles. Normally when
impulses travel down the nerve, the nerve endings release a neurotransmitter
substance called acetylcholine. In myasthenia gravis, antibodies
produced by the body's own immune system block, alter, or destroy
the receptors for acetylcholine.
Types of Myasthenia gravis
Myasthenia gravis can be classified according to which skeletal
muscles are affected. Within a year of onset, approximately 85–90%
of patients develop generalized myasthenia gravis, which is characterized
by weakness in the trunk, arms, and legs.
About 10–15% of patients have weakness only in muscles that
control eye movement. This type is called ocular myasthenia
Other types of MG include congenital, which is
an inherited condition caused by genetic defect, and transient neonatal,
which occurs in infants born to mothers who have MG. Congenital
MG develops at or shortly after birth and causes generalized symptoms.
Transient neonatal MG is a temporary condition
that develops in 10–20% of infants born to mothers who have
MG. Transient neonatal MG is caused by circulation of the mother’s
antibodies through the placenta and it lasts as long as the mother’s
antibodies remain in the infant (usually a few weeks after birth).
Incidence and Prevalence of Myasthenia gravis
Myasthenia gravis affects approximately 2 out of every 100,000
people and can occur at any age. It is most common in women between
the ages of 18 and 25. In men, the condition usually develops between
60 and 80 years of age.
Symptoms of Myasthenia gravis
Initially, people with myasthenia gravis may complain about specific
muscle weakness, particularly in the eyes, face and neck. They may
have difficulty swallowing, chewing or speaking, and may have double
vision. They also may feel fatigue, especially later in the day.
Symptoms can be aggravated by emotional stress, systemic illness
such as a viral respiratory infection, menstrual cycle, pregnancy,
hypothyroidism or hyperthyroidism, and other factors.
Myasthenia gravis Treatment
Myasthenia gravis can be controlled. Some medications (Cholinesterase
inhibitors, such as pyridostigmine (Mestinon) and corticosteroids)
improve neuromuscular transmission and increase muscle strength,
and some suppress the production of abnormal antibodies. These medications
must be used with careful medical followup because they may cause
major side effects. Thymectomy, the surgical removal of the thymus
gland (which often is abnormal in myasthenia gravis patients), improves
symptoms in certain patients and may cure some individuals, possibly
by re-balancing the immune system. Other therapies include plasmapheresis,
a procedure in which abnormal antibodies are removed from the blood,
and high-dose intravenous immune globulin, which temporarily modifies
the immune system and provides the body with normal antibodies from
Homeopathy Treatment & Homeopathic Remedies for Myasthenia
Homeopathy treats the person
as a whole. It means that homeopathic treatment focuses on the patient
as a person, as well as his pathological condition. The homeopathic
medicines are selected after a full individualizing examination
and case-analysis, which includes the medical history of the patient,
physical and mental constitution etc.
Following homeopathic medicines
have been found effective in many cases of Myasthenia gravis:
Alumina, Conium Gelsemium
The following medicines may also prove useful according to the
Zincum, Cabo-an, Niccolum, Psorinum, Sepia, Guare, Cadmium,